Detalhe da pesquisa
1.
Sirt6 ablation in the liver causes fatty liver that increases cancer risky by upregulating Serpina12.
EMBO Rep
; 25(3): 1361-1386, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38332150
2.
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks.
Cell
; 141(2): 243-54, 2010 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-20362325
3.
Machine learning model for anti-cancer drug combinations: Analysis, prediction, and validation.
Pharmacol Res
; 194: 106830, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37343647
4.
Function of DHX33 in promoting Warburg effect via regulation of glycolytic genes.
J Cell Physiol
; 236(2): 981-996, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32617965
5.
BRCA1 represses DNA replication initiation through antagonizing estrogen signaling and maintains genome stability in parallel with WEE1-MCM2 signaling during pregnancy.
Hum Mol Genet
; 28(5): 842-857, 2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30445628
6.
SRC-3, a Steroid Receptor Coactivator: Implication in Cancer.
Int J Mol Sci
; 22(9)2021 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33946224
7.
Optimizing CRISPR/Cas9 technology for precise correction of the Fgfr3-G374R mutation in achondroplasia in mice.
J Biol Chem
; 294(4): 1142-1151, 2019 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30487289
8.
Single-cell RNA-Seq reveals cell heterogeneity and hierarchy within mouse mammary epithelia.
J Biol Chem
; 293(22): 8315-8329, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29666189
9.
Analysis of Genomes and Transcriptomes of Hepatocellular Carcinomas Identifies Mutations and Gene Expression Changes in the Transforming Growth Factor-ß Pathway.
Gastroenterology
; 154(1): 195-210, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28918914
10.
Sexual Fate Change of XX Germ Cells Caused by the Deletion of SMAD4 and STRA8 Independent of Somatic Sex Reprogramming.
PLoS Biol
; 14(9): e1002553, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27606421
11.
A HIF-1 target, ATIA, protects cells from apoptosis by modulating the mitochondrial thioredoxin, TRX2.
Mol Cell
; 42(5): 597-609, 2011 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-21658601
12.
SMAD3 Regulates Follicle-stimulating Hormone Synthesis by Pituitary Gonadotrope Cells in Vivo.
J Biol Chem
; 292(6): 2301-2314, 2017 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27994055
13.
A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency.
Mol Cell
; 35(4): 534-41, 2009 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-19716796
14.
Tumor suppressor p53 cooperates with SIRT6 to regulate gluconeogenesis by promoting FoxO1 nuclear exclusion.
Proc Natl Acad Sci U S A
; 111(29): 10684-9, 2014 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25009184
15.
Tak1, Smad4 and Trim33 redundantly mediate TGF-ß3 signaling during palate development.
Dev Biol
; 398(2): 231-41, 2015 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25523394
16.
Nodal/activin signaling promotes male germ cell fate and suppresses female programming in somatic cells.
Development
; 140(2): 291-300, 2013 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23221368
17.
Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis.
Mol Cell
; 32(1): 11-20, 2008 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-18851829
18.
RNA interference and inhibition of MEK-ERK signaling prevent abnormal skeletal phenotypes in a mouse model of craniosynostosis.
Nat Genet
; 39(9): 1145-50, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17694057
19.
Synergistic therapeutic effect of cisplatin and phosphatidylinositol 3-kinase (PI3K) inhibitors in cancer growth and metastasis of Brca1 mutant tumors.
J Biol Chem
; 289(35): 24202-14, 2014 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-25006250
20.
FGFR3 induces degradation of BMP type I receptor to regulate skeletal development.
Biochim Biophys Acta
; 1843(7): 1237-47, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24657641